• Includes excerpts from firsthand accounts of explorers and colonists associated with Roanoke and Jamestown.
• Explains the relationship between John Smith and Pocahontas.
• Discusses the theories and evidence about what happened to the lost colony.

Nearly 20 years before Jamestown was settled, the English established one of the earliest colonies in North America around the Chesapeake Bay region; the colony had over 100 inhabitants. Like other early settlements, Roanoke struggled to survive in its infancy, to the extent that the colony's leader, John White, sailed back to England in 1587 in an effort to bring more supplies and help. However, the attempts to bring back supplies were thwarted by the Spanish in the midst of the Anglo-Spanish War, and it was not until 1590 that White reached Roanoke again.

What White found when he came back to Roanoke led to one of the most enduring mysteries in American history. Despite the fact he left over 100 people in Roanoke in 1587, White returned to literally nothing, with all traces of the settlement gone and no evidence of fighting or anything else that might have explained the disappearance of the inhabitants. White found the word "Croatoan" carved on a tree nearby, which he figured might mean the colonists moved to a nearby island, but he was unable to conduct a search expedition there. The Spanish also searched for the colony in hopes of wiping it out themselves, but none of the Europeans could find Roanoke's colonists or explain what happened to the "lost" colony.

The fate of Roanoke has fascinated people for over 400 years, and there is no shortage of theories regarding the disappearance of the colony.