Dr. Alexis Ortega is board-certified in longevity, regenerative and aesthetic medicine. He has a clinic Ad Astra in Barcelona, Spain.

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Timestamps:

00:00 Intro

00:55 How to counteract age-related loss of facial harmony aside from just wrinkles

12:30 Does growth hormone change the face

18:10 Bon Charge sponsorship

19:17 What's the minimum effective dose of at-home skincare — the three things that actually move the needle?

21:28 Retinoids

24:05 Skin barrier support

27:00 Effect of sun exposure on extrinsic skin aging

31:02 Best evidence-based sunscreen ingredients

34:34 List of best sunscreen ingredients

36:00 Worst sunscreen ingredients

37:45 Daily sunscreen vs using the UV index as a guide

39:43 Do people overuse skincare products

42:33 Castor oil, beef tallow and egg yolks for skin

49:08 Are natural sunscreens effective

49:59 If someone had unlimited money today, what are the most promising rejuvenation interventions actually available?

51:08 What diagnostics Alexis would do with an unlimited budget

54:30 Rejuvenation therapies Alexis would do

55:18 Alexis approach to peptides

56:00 Intravenous senolytics

56:20 NAD injections

57:14 What you can do now to practically extend lifespan

59:40 Intravenous exosomes

01:00:25 Therapeutic plasma exchange

01:03:06 Stem cell therapy

01:05:30 Gene therapies

01:07:48 What biomarkers matter most for predicting long-term health

Alexis Ortega MD Instagram: https://www.instagram.com/alexis_ortega_md/