Episodes

  • Can a Six Pack Protect Your Brain from Alzheimer's? | Drs. Oak Sixpack & Josh Helman | #64

    Can a Six Pack Protect Your Brain from Alzheimer's? | Drs. Oak Sixpack & Josh Helman | #64
    May 16 2026
    For personalized guidance and support with reversing & preventing Alzheimer's, you can reach out to Dr. Josh Helman directly. Visit his website at http://drjosh.com or contact his office at (407) 221-8841 to learn more about how he can help your journey to a healthier brain. Dr. Oak can be reached via his website: https://linktr.ee/doctorsixpack. What if one of the best ways to protect your brain and lower your Alzheimer’s risk is simply building more muscle? In this special LIVE in-studio episode, Dr. Josh Helman sits down with Dr. Oak — also known online as “Dr. Sixpack” — for a powerful conversation about longevity, brain health, exercise, inflammation, metabolism, and Alzheimer’s prevention. Dr. Oak is a physician from Thailand, a lifestyle medicine expert, and a fitness educator with millions of followers on social media. Together, they discuss the surprising connection between muscle and brain function, why visceral fat is so dangerous, and how lifestyle changes may dramatically reduce the risk of cognitive decline. Topics covered in this episode include: 00:00 – Muscle, Visceral Fat & Brain Health 00:00:41 – Meet Dr. Oak (Dr. Sixpack) 00:05:46 – Why Muscle Matters for Longevity 00:08:36 – Best Strength Training for Seniors 00:15:34 – Injury Recovery & Safe Weightlifting 00:17:05 – Cardio, HIIT & VO2 Max Benefits 00:21:37 – Weighted Vests, Pull-Ups & Joint Health 00:28:43 – Alzheimer’s Rise in Thailand 00:33:06 – Sugar, Diet & Brain Inflammation 00:36:27 – Parasites & Brain Health Risks 00:40:35 – Preventing Alzheimer’s With Lifestyle Medicine 00:43:47 – Reversing Diabetes & Fatty Liver Naturally 00:49:17 – Discovering Lifestyle Medicine 00:51:56 – The Dark Side of Professional Bodybuilding 00:57:41 – Traditional Thai Diet & Longevity Foods 01:00:19 – Dr. Oak’s Top Alzheimer’s Prevention Tips 01:01:59 – Why Regular Health Checkups Matter 01:02:40 – Finding the Right Diet for Your Body 01:03:05 – Why Everyone Should Lift Weights 01:04:03 – Where to Find Dr. Oak Online 01:05:20 – Final Thoughts on Prevention & Longevity 01:07:02 – Invitation to Visit Thailand & Closing Message Dr. Oak also shares practical advice for: ✔ Beginners starting resistance training ✔ Seniors with joint pain ✔ Improving balance and mobility ✔ Reducing inflammation naturally ✔ Building sustainable healthy habits Whether you’re focused on Alzheimer’s prevention, reversing metabolic disease, improving fitness, or simply aging better, this episode is packed with actionable insights. #Alzheimers #BrainHealth #Longevity #DrJoshHelman #DrOak Connect with Dr. Josh Helman, MD: Instagram - / greenbrainsmd Facebook - / greenbrainsmd LinkedIn - / doctorjosh TikTok - / greenbrainsmd YouTube - / @greenbrainsmd Others - https://linktr.ee/greenbrainsmdDisclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.
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    1 hr and 8 mins
  • Can Hyperbaric Oxygen Help Alzheimer’s & Brain Injury? Drs. Paul Harch & Josh Helman #HBOT

    Can Hyperbaric Oxygen Help Alzheimer’s & Brain Injury? Drs. Paul Harch & Josh Helman #HBOT
    May 14 2026
    For personalized guidance and support with Hyperbaric Oxygen Therapy (HBOT), you can reach out to Dr. Josh Helman directly. Visit his website at http://drjosh.com or contact his office at (407) 221-8841 to learn more about how he can help you on your journey to a healthier brain. Dr. Harch can be reached via his website: http://HBOT.com. Discover the science behind Hyperbaric Oxygen Therapy (HBOT) for Alzheimer’s disease, dementia, traumatic brain injury (TBI), and brain recovery in this powerful interview with Dr. Paul Harch, one of the world’s leading experts in hyperbaric medicine. Most people think hyperbaric oxygen therapy is only used for scuba divers, carbon monoxide poisoning, or wound healing—but Dr. Paul Harch explains why HBOT may have much broader applications for neurological conditions including Alzheimer’s, memory loss, cognitive decline, stroke recovery, autism, PTSD, concussion, and chronic brain injury. In this episode of Alzheimer’s Breakthrough, Dr. Josh and Dr. Harch discuss how HBOT works, why pressure + oxygen both matter, and how proper dosing can improve brain blood flow, reduce neuroinflammation, support neuroplasticity, and potentially help repair injured brain tissue. Topics covered include: 0:00 Introduction to HBOT 6:00 The Journey into Hyperbaric Oxygen 12:35 Research and Imaging Techniques 19:05 Dosing and Treatment Protocols 26:12 Individual Treatment Approaches 33:52 Contraindications and Patient Considerations 42:15 Understanding QEEG and Dosing in Hyperbaric Therapy 42:35 Impact of Hyperbaric Oxygen on Neurological Conditions 44:36 Mechanism of Action: How Hyperbaric Oxygen Works 47:30 Challenges and Limitations in Treating ALS 49:15 Exploring Hydrogen Gas & Its Potential 50:36 Trauma & Hyperbaric Oxygen: Adjusting Protocols 53:19 Finding Qualified Practitioners 56:22 Future of Hyperbaric Medicine 59:47 Key Takeaways & Final Thoughts Dr. Paul Harch is the co-author of The Oxygen Revolution and has spent over 40 years researching and treating neurological disorders using hyperbaric oxygen therapy. If you're interested in Alzheimer’s prevention, dementia treatment, brain optimization, functional medicine, longevity, and advanced neurological therapies, this episode is for you. Please like, subscribe, and share with someone who may benefit. #HyperbaricOxygenTherapy #HBOT #Alzheimers #Dementia #BrainHealth #TBI #ConcussionRecovery #CognitiveDecline #Neuroplasticity #MemoryLoss #DrPaulHarch #FunctionalMedicine #BrainHealing #AlzheimersTreatment #neurology Connect with Dr. Josh Helman, MD: Instagram - / greenbrainsmd Facebook - / greenbrainsmd LinkedIn - / doctorjosh TikTok - / greenbrainsmd YouTube - / @greenbrainsmd Others - https://linktr.ee/greenbrainsmdDisclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.
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    1 hr and 7 mins
  • Doctors Reveal the EARLY Signs of Alzheimer’s (Before Memory Loss) With Dr. Melissa Murray

    Doctors Reveal the EARLY Signs of Alzheimer’s (Before Memory Loss) With Dr. Melissa Murray
    Mar 26 2026
    What if Alzheimer’s isn’t just one disease but a family of diseases? In this episode, I’m thrilled to be joined by Dr. Melissa Murray, a professor of neuroscience at the Mayo Clinic. Dr. Murray’s groundbreaking research focuses on Alzheimer’s, dementia with Lewy bodies, and other neurodegenerative conditions. She leads the Mayo Clinic’s Translational Neuropathology Lab, where her team combines neuropathology, neuroimaging, and genetics to understand these diseases better.Dr. Murray is one of the recent winners of the Rainwater Prize for Outstanding Innovation in Neurodegenerative Research, which came with a $400,000 prize to further her and her colleague Dr. Dennis Dickson's research at Mayo Clinic.The Rainwater Prize honors scientific contributions to the field of neurodegenerative research that focus on diseases associated with the accumulation of tau protein in the brain, with the goal of translating discoveries into meaningful therapeutic and diagnostic innovations.Today’s discussion tackles a critical issue in brain health: treating Alzheimer’s like it’s a single disease. With advances in neuroimaging and biomarkers, we can now diagnose Alzheimer’s while people are still alive, which is a huge step forward from the past. Dr. Murray also highlights how brain donation is helping researchers like her gain deeper insights into the causes and progression of Alzheimer’s.“We can't help our genetics. We're blessed with what we were given, but we also get to play that deck of cards that we're handed, and we have a chance to make a difference.” ~ Melissa Murray, PhDIn this Episode03:47 - The power of neuroimaging and biomarkers for early Alzheimer’s detection05:58 - Alzheimer’s disease is not a single condition06:54 - Understanding vascular contributions to Alzheimer’s in younger patients12:20 - How lifestyle and genetics influence Alzheimer’s development13:32 - The future of Alzheimer’s diagnostics: Imaging modalities20:15 - Brain research and the role of brain donation in advancing research40:37 - Studying the brain for infection (viruses, bacteria, or parasites)49:44 - The connection between sleep and the risk of developing Alzheimer’s57:51 - Ongoing research about Alzheimer's and brain health1:00:18 - Key takeaways from the discussionResources:- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide- Book: The Tale of the Dueling Neurosurgeons by Sam Kean - https://www.amazon.com/dp/0316182354- MRI and pathology of REM sleep behavior disorder in dementia with Lewy bodies - https://pmc.ncbi.nlm.nih.gov/articles/PMC3812105/Connect with Melissa Murray, PhD: - LinkedIn - https://www.linkedin.com/in/melissa-e-murray-012a919/- Website - https://www.mayo.eduConnect with Dr. Josh Helman, MD:- Instagram - https://www.instagram.com/greenbrainsMD- Facebook - https://www.facebook.com/greenbrainsmd/- LinkedIn - https://www.linkedin.com/in/doctorjosh- TikTok - https://www.tiktok.com/@greenbrainsmd- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1- Others - https://linktr.ee/greenbrainsmdDisclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.
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    1 hr and 4 mins
  • Preventing Alzheimer’s: Diet, Air Pollution & Brain Health | Dr. Austin Perlmutter

    Preventing Alzheimer’s: Diet, Air Pollution & Brain Health | Dr. Austin Perlmutter
    Mar 19 2026
    Could simple lifestyle changes be the key to preventing Alzheimer’s? In this episode, I’m joined by Dr. Austin Perlmutter, a physician, researcher, and New York Times best-selling author. Dr. Perlmutter's work focuses on Alzheimer's prevention and how our everyday choices impact long-term brain health. His unique approach blends neuroscience, lifestyle medicine, and environmental health.Dr. Perlmutter explains how inflammation in the brain often leads to cognitive decline, and why it’s essential to focus on prevention before reaching the point of irreversible damage. He highlights lifestyle interventions, such as regular exercise, eating a minimally processed diet, and getting out in nature. He also discusses the importance of air quality, which many people overlook as a major factor in brain health.We explore practical ways to mitigate these risks and optimize cognitive function for decades to come, so if you're looking for actionable steps to protect your brain and reduce Alzheimer's risk, this episode has the insights you need.“I think we’ve seen some pretty compelling literature suggesting that simply exposing yourself to or getting out in nature is a health intervention, particularly for the brain.” ~ Dr. Austin Perlmutter In this Episode07:09 - The chronic disease crisis and brain health09:16 - Chronic inflammation as a major driver of Alzheimer’s10:34 - The importance of inflammation management in Alzheimer's prevention20:40 - Diet and air quality for Alzheimer’s prevention21:44 - Air pollution: the hidden threat affecting brain health29:19 - Polyphenols and their protective impact on brain health36:01 - How nature exposure can reduce stress and improve cognitive function43:19 - Dr. Perlmutter's diet for long-term health50:49 - Recommended supplements for optimal health52:33 - Dr. Perlmutter's final thoughts on protecting your brainResources:- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide- Brain Wash by Dr. Austin Perlmutter & Dr. David Perlmutter - https://drperlmutter.com/books/brain-wash/Connect with Dr. Austin Perlmutter: - Website - https://austinperlmutter.com- YouTube - https://www.youtube.com/@draustinperlmutter- Instagram - https://www.instagram.com/draustinperlmutter/Connect with Dr. Josh Helman, MD:- Instagram - https://www.instagram.com/greenbrainsMD- Facebook - https://www.facebook.com/greenbrainsmd/- LinkedIn - https://www.linkedin.com/in/doctorjosh- TikTok - https://www.tiktok.com/@greenbrainsmd- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1- Others - https://linktr.ee/greenbrainsmdDisclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.
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    58 mins
  • Can Ketones Reverse Alzheimer’s? What the Research Really Shows With Dr. Elizabeth Yurth

    Can Ketones Reverse Alzheimer’s? What the Research Really Shows With Dr. Elizabeth Yurth
    Mar 12 2026
    Are ketones just a diet trend, or could they be the game-changer in Alzheimer's treatment? In this episode, I’m joined by Dr. Elizabeth Yurth, co-founder and chief medical officer of Boulder Longevity Institute. Dr. Yurth has been a pioneer in regenerative medicine, and she shares insights on how ketones can support brain health, particularly for people with Alzheimer's and cognitive decline.We talk about the role of these powerful molecules in improving brain function and performance, and how, when used properly, ketones can help patients feel sharper and more functional, even despite cognitive decline. Plus, Dr. Yurth discusses her approach to dosing ketones for maximum effect, using them periodically throughout the day to maintain cognitive energy levels.If you're looking to understand how ketones can support brain health or are wondering if they can help with Alzheimer's, this episode provides a detailed, science-backed answer.“Ketones are not just a diet trend or a shortcut, but rather a human metabolic pathway. When used thoughtfully, exogenous ketones are going to completely support cellular energy, make your mitochondria efficient, and give you metabolic resistance.” ~ Dr. Elizabeth YurthIn this Episode02:15 - The role of ketones in metabolism and brain energy05:31 - The importance of mitochondria in energy production08:00 - Ketones and gut health10:46 - Common misconceptions about ketones15:50 - Ketones in Alzheimer’s treatment and mitochondrial efficiency29:58 - Dosing ketones: How much and when for optimal brain support43:20 - How soon can we see the positive effects of ketones?45:03 - New developments in brain health devices50:02 - Key takeaways and final thoughts on ketones for brain healthResources:- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide- Try Kenetik, Dr. Josh’s favorite ketones, for 25% off (limited time) - https://drinkkenetik.com/DRJOSH. Discount Code: DRJOSHConnect with Dr. Elizabeth Yurth:- Website - https://boulderlongevity.com/- BLI Academy Website - https://bli.academy/- Instagram - https://www.instagram.com/dryurthConnect with Dr. Josh Helman, MD:- Instagram - https://www.instagram.com/greenbrainsMD- Facebook - https://www.facebook.com/greenbrainsmd/- LinkedIn - https://www.linkedin.com/in/doctorjosh- TikTok - https://www.tiktok.com/@greenbrainsmd- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1- Others - https://linktr.ee/greenbrainsmdDisclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.
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    58 mins
  • Boost Memory While You Sleep (No Pills Needed) With Dr. Michael Leon

    Boost Memory While You Sleep (No Pills Needed) With Dr. Michael Leon
    Mar 5 2026
    Did you know that your sense of smell can affect your brain function? In this episode, I sit down with Dr. Michael Leon, a professor emeritus of neurobiology and behavior at UC Irvine, to discuss a fascinating, yet simple intervention that can improve memory and brain function: olfactory enrichment. We explore how odors, when introduced during sleep, can trigger dramatic improvements in verbal memory and even stimulate changes in the brain's memory circuits.Dr. Leon dives into his research on the relationship between the sense of smell and the brain's memory pathways. He explains how olfactory loss is linked to various neurodegenerative conditions, such as Alzheimer's, and how reintroducing odors during sleep can have a profound impact on cognitive function. We also discuss the development of a device, the Memory Air, which makes olfactory enrichment easily accessible at home.This conversation sheds light on how olfactory stimulation can provide a simple, non-invasive, and safe solution to brain health and memory loss.“The sense of smell is the only sense that has a superhighway access to the memory centers and the emotional centers of your brain.” ~ Dr. Michael LeonIn this Episode03:28 - How the sense of smell differs from the other senses09:19 - Scent-related marketing strategies09:57 - Study results and brain imaging findings19:31 - Potential benefits of olfactory stimulation for other medical conditions29:03 - Selecting the right scent and avoiding artificial odors36:30 - Olfactory training for people who have lost their sense of smell37:37 - Development and use of the Memory Air device47:43 - Dr. Leon's thoughts on plastics getting into the brain49:19 - The most misunderstood information about smell and the brain50:56 - Dosage, duration, and schedule for safe and effective useResources:- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide- UC Irvine discovery leads to TIME-honored memory device - https://news.uci.edu/2025/10/09/uc-irvine-discovery-leads-to-time-honored-memory-device/- Get Your Memory Air Device - https://memoryair.com/discount/DRJOSHConnect with Dr. Michael Leon: - UCI Directory - https://directory.uci.edu/people/mleonConnect with Dr. Josh Helman, MD:- Instagram - https://www.instagram.com/greenbrainsMD- Facebook - https://www.facebook.com/greenbrainsmd/- LinkedIn - https://www.linkedin.com/in/doctorjosh- TikTok - https://www.tiktok.com/@greenbrainsmd- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1- Others - https://linktr.ee/greenbrainsmdDisclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.
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    58 mins
  • The Nobel Prize Molecule That Could Prevent Alzheimer’s & Extend Your Life: ESS60 Explained With Chris Burres

    The Nobel Prize Molecule That Could Prevent Alzheimer’s & Extend Your Life: ESS60 Explained With Chris Burres
    Feb 26 2026
    Can a molecule discovered in 1985 hold the key to longevity and brain health? In this episode, I have the privilege of speaking with Chris Burres, the Chief Science Officer at MyVitalC, about ESS60, an extraordinary molecule shown to support longevity, brain health, and mitochondrial function. Discovered in 1985 and awarded the Nobel Prize in 1996, ESS60, also known as carbon-60, is now being explored for its potential health benefits, particularly for neurodegenerative conditions such as Alzheimer’s disease.Chris shares the story behind the discovery of this molecule and why it has generated such excitement across different fields. ESS60 has demonstrated impressive results in animal studies, including a 90% increase in lifespan, and shows promise in reducing oxidative stress and supporting detoxification.We also discuss how ESS60 works in the body, particularly in relation to mitochondria, and why it could be a game-changer for brain health. From its antioxidant properties to its role in detoxification and mitochondrial repair, ESS60 could play a significant role in Alzheimer’s prevention.Don’t miss this deep dive into one of the most fascinating molecules in modern science—one that could shape the future of brain health and longevity.“Interestingly, the molecule (ESS60) is amazing. The reason it won the Nobel Prize is that it performs as well or better than the current best materials in almost every application.” ~ Chris BurresIn this Episode02:40 - The discovery of this amazing molecule03:48 - The longevity experiment: Wistar rats live 90% longer05:47 - ESS60 and why it’s safe for human consumption14:43 - How ESS60 is manufactured: Chris explains its characteristics22:15 - ESS60’s role in mitochondria and brain health29:27 - Safety considerations and dosage recommendations for ESS6036:14 - Testimonials: better sleep, energy, and mental focus with ESS6040:54 - Why olive oil is the ideal carrier for ESS6050:05 - Key takeaways from today’s episode52:00 - How often does Chris consume ESS60?Resources:- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide- Book: Why We Sleep by Matthew Walker - https://www.amazon.com/dp/1501144316- Bulletproof Coffee by Dave Asprey - https://www.bulletproof.com/coffee/Connect with Chris Burres: - Website - https://www.myvitalc.com/Connect with Dr. Josh Helman, MD:- Instagram - https://www.instagram.com/greenbrainsMD- Facebook - https://www.facebook.com/greenbrainsmd/- LinkedIn - https://www.linkedin.com/in/doctorjosh- TikTok - https://www.tiktok.com/@greenbrainsmd- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1- Others - https://linktr.ee/greenbrainsmdDisclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.
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    56 mins
  • Can Blood Filtration Reverse Post-Viral Inflammation and Brain Fog? With Dr. Mobeen Syed

    Can Blood Filtration Reverse Post-Viral Inflammation and Brain Fog? With Dr. Mobeen Syed
    Feb 19 2026
    Can “blood filtration” act like an oil change for chronic inflammation? In this episode, Dr. Mobeen Syed, also known as Dr. Been, returns to discuss a hot topic in chronic inflammation and spike-related syndromes: therapeutic plasma exchange (TPE) and other blood filtration approaches. We break down what these procedures actually do, what they can remove from circulation, and why that might matter for brain fog, fatigue, microvascular dysfunction, and neuroinflammation.Dr. Been outlines the core methods: classic plasma exchange, immunoadsorption, and other extracorporeal options. We discuss the proposed “reset” effect, including reducing inflammatory mediators, autoantibodies, and abnormal clotting signals that may keep the body stuck in a vicious cycle.We review a sham-controlled randomized trial that found TPE to be safe but ineffective in that cohort, and discuss why a single intervention may help only a subset, if at all.If you want a clear, mechanism-first explanation without the hype, this conversation is for you. Share it with someone experiencing brain fog or fatigue, and subscribe for more evidence-based brain health deep dives.“Normally, the body is very efficient in removing extraneous harmful substances. When the body is unable to remove them because they are difficult to remove (like beta-pleated fiber sheets) and they are being produced a lot, we need to give the body a break. So we clean out the plasma.” ~ Dr. Mobeen Syed, MD, MScIn this Episode03:16 - Dr. Been's opinion on the benefits of TPE05:02 - Can we remove bad things from the blood?11:44 - The core idea: dislodge first, filter after24:04 - What the studies say about TPE49:41 - Can TPE reverse the effects of chronic inflammation and spike protein?53:58 - Clarification of concepts and terminologies discussed1:02:17 - Key takeaway from today's episodeResources:- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide- Therapeutic Plasma Exchange: Current and Emerging Applications to Mitigate Cellular Signaling in Disease - https://www.mdpi.com/2218-273X/15/7/1000- Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin - https://pmc.ncbi.nlm.nih.gov/articles/PMC8381139/- Functional autoantibodies against G-protein coupled receptors in patients with persistent Long-COVID-19 symptoms - https://pubmed.ncbi.nlm.nih.gov/33880442/Connect with Dr. Mobeen Syed, MD, MSc: - Website - https://members.drbeen.com/courses- YouTube - https://www.youtube.com/@DrBeenMedicalLecturesConnect with Dr. Josh Helman, MD:- Instagram - https://www.instagram.com/greenbrainsMD- Facebook - https://www.facebook.com/greenbrainsmd/- LinkedIn - https://www.linkedin.com/in/doctorjosh- TikTok - https://www.tiktok.com/@greenbrainsmd- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1- Others - https://linktr.ee/greenbrainsmdDisclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.
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    1 hr and 6 mins