ENGLISH Constapation and Parkinson's
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ENGLISH Constapation and Parkinson's
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Summary
Executive Summary www.ParkinsonTherapy.com
Constipation is one of the most prevalent and debilitating non-motor symptoms of Parkinson’s disease (PD), affecting between 20% and 80% of patients. It frequently serves as a prodromal marker, appearing up to 20 years before the onset of cardinal motor symptoms. The condition is primarily driven by the deposition of alpha-synuclein in the enteric nervous system (ENS) and damage to the autonomic nervous system, which regulates involuntary muscle movements in the intestinal tract.
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