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Some women aren't losing weight on max-dose GLP-1s — and the fix is dosing down, not pushing harder.

Ana Reisdorf, registered dietitian and GLP-1 user, sits down with Alex Mufson, LCSW and founder of Canary House, to unpack why high-functioning women show up as non-responders on Ozempic, Wegovy, and Zepbound. They cover the labs traditional medicine misses, why under-eating sabotages results, and how regulating the body — not suppressing appetite — is what actually moves the scale.

IN THIS EPISODE
- Why some non-responders lose more on a microdose of tirzepatide than on a maximum dose
- The ferritin, fasting insulin, and Dutch Plus markers most GLP-1 prescribers don't run
- The glucose-insulin mismatch behind weight gain that "doesn't make sense"
- Why appetite suppression isn't the goal of GLP-1 therapy — and can stall fat loss entirely
- How epigenetics, survival mode, and high-functioning caretaker patterns block GLP-1 response

ABOUT THE GUEST
Alex Mufson, a Licensed Clinical Social Worker, is the founder of Canary House, an integrative healing practice specializing in high-functioning individuals living with persistent exhaustion, pain, and unexplained symptoms despite normal or inconclusive labs. Her work focuses on nervous, immune, and metabolic regulation for people whose lives appear stable on paper but feel increasingly effortful from the inside.

CONNECT WITH ALEX
Website: https://www.canaryhousehealing.com/
Substack: https://alexmufson.substack.com/
LinkedIn: https://www.linkedin.com/in/alex-mufson-lcsw-96146b29/
Instagram: @alex.mufson, @canaryhousehealing

SPONSOR
Folly — Hair support gummies for GLP-1 users. A 300-person study showed less shedding and fuller hair after 4 weeks.
FollyNutrition.com — code GLP1HUB for 20% off

📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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Before Ozempic was a weight-loss story, it was a diabetes drug - and at diabetes doses, it behaves nothing like the version you've heard about.

Registered dietitian Ana Reisdorf sits down with diabetes specialist Christa Brown, RD, to unpack what GLP-1s actually do for type 2 diabetes - and why they rarely cause the blood sugar crashes other diabetes meds do. They cover dosing, A1C, nutrition, and the lifestyle pieces still doing real work alongside the medication.

IN THIS EPISODE

• How GLP-1s lower A1C without causing dangerous low blood sugar - the four-mechanism breakdown
• Mounjaro vs. Ozempic: how diabetes dosing actually differs from weight-loss dosing
• Why type 2 diabetes patients shouldn't fear carbs on Ozempic, Wegovy, or Mounjaro
• The vitamin D, magnesium, and B12 deficiencies behind GLP-1 fatigue, and what to take
• Adaptogens, sleep hygiene, and the lifestyle moves that quietly improve blood sugar on their own

ABOUT OUR GUEST
Christa Brown is a Registered Dietitian and nutrition expert specializing in diabetes, prediabetes, PCOS, and GLP-1 medication support. In addition to working with individual patients, she partners with healthcare practices and organizations to provide nutrition consulting, menu analysis, and workplace wellness support. She has been featured in EatingWell, Good Housekeeping, Women's Health, Real Simple, Business Insider, People, and Parade. Christa has her practice in Woodbridge, NJ and also sees clients across New Jersey virtually.

CONNECT WITH CHRISTA
Website: https://www.christabrowndietitian.com
LinkedIn: https://www.linkedin.com/in/christabrowndietitian/

📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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You're losing weight on a GLP-1 - so why is starting to exercise still the part you can't make stick? And why does every workout program feel like too much, too fast, the second you actually try?

Casey Sines, certified personal trainer and Brello Rise functional training and cardio expert, joins Ana to explain why tiny starting points and habit stacks beat lofty fitness goals - especially when bad knees, packed schedules, and decades of all-or-nothing thinking are all working against you.

About the guest:
Casey is a NASM-certified personal and group fitness trainer specializing in cardio, strength, and agility training. She is an on-camera coach with Brello Rise, where she leads dynamic functional training, cardio workouts, and recovery sessions. In addition to her work with Brello, Casey has coached across a global portfolio of fitness platforms, including Fitbit, iFit, TRX, FitXR, Aaptiv, Katalyst, and more.

Connect with Casey at https://brellohealth.com | Instagram: @brellorise

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🤝 This episode is sponsored by Brello Health
Online wellness care plans for women, including GLP-1 and NAD+ therapies under medical provider guidance. Learn more at https://www.brellohealth.com/

🤝Also sponsored by Maeva - Use the code is ANA15 to get 15% off your order at http://maeva.co

and 🤝Folly - Visit https://follynutrition.com/GLP1HUB to get your hair health gummies

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📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.