Dr. Chris Rhodes explains what fasting is actually doing in the body, where the benefits begin, and why shorter fasting windows may not deliver what many people expect. He walks us through the science behind fasting mimetics, including how his team studied a 36-hour fast and built a supplement around the molecules that arise during it. You come away with a clearer way to think about hunger control, food noise, metabolic health, and the tradeoffs between fasting, appetite-suppressing drugs, and everyday eating. He also offers a sharp take on saturated fat hype and makes the case for a more personal, evidence-based future in nutrition.

Big Announcement: The Super Age Games are here! Join us November 7th in NYC for an entirely new longevity competition.

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LMNT Electrolytes: Our #1 electrolytes for optimal hydration, and their new 12oz sparkling cans are officially for sale online! Get a free Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Fatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and Fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.

Our Place: The top cookware brand for beautiful, non-toxic, PFA-free pots and pans. Use the code “AGEIST” for 10% off at fromourplace.com.

Key Moments

"What most people do not realize is that they are often not getting the benefits of fasting that they think that they are getting."

“From a biological perspective, it takes around 24 hours without food in order to actually activate that metabolic switch where you're going from, you know, fed metabolism, glucose metabolism, over into ketone metabolism and fasting metabolism.”

"Let's find patterns that work specifically for you."

Connect with Chris Rhodes

Website: mimiohealth.com

LinkedIn: linkedin.com/in/chrishrhodes

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Looking for quick strategies for building sustainable fitness habits? This week, we revisit a conversation with former firefighter-turned-osteopath and author David Vaux, where he shares wisdom from a lifetime of grit and strength. We all know that muscle mass will greatly improve our healthspan, but the perfect way to build and maintain that strength can be elusive. Get the inside scoop on balancing physical challenges with proper recovery. Find key guidance on staying fit and resilient, no matter your age.

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Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 20% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist.

LMNT Electrolytes – Our #1 electrolytes for optimal hydration, and their new 12oz sparkling cans are officially for sale online! Get a free Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Our Place – our favorite cookware brand for non-toxic, PFA-free pots and pans. Use code AGEIST for 10% off at fromourplace.com

Key Quotes

“Fast-twitch fibers are the currency of healthy aging.”

“It's not about becoming injured or burnt out; it's about consistency.”

“Strength training is like brushing your teeth: something you just do.”

Connect with David Vaux

Book Stronger: How to Build Strength, The Secret to a Longer, Healthier Life

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Donnie Moss explains how she went from cardio-only routines to strength training at 55 and why she now pushes “move every day” as the baseline for feeling better. She shares a practical approach built around short, doable workouts that help midlife women rebuild consistency without making fitness an all-or-nothing identity. The conversation also gets real about menopause symptoms that can feel scary when nobody has named them, plus how mindset and self-talk can shape follow-through. You’ll leave with simple starting points, a clearer way to measure progress, and the motivation to take one small step today that stacks into momentum.

Special Thanks to Our Sponsors

Puori Grass Fed Whey Protein: 21g of whey protein per serving from grass-fed cows, with 6g BCAAs and 2.4g leucine, free from hormones, GMOs, and pesticides. Use code AGEIST at puori.com/AGEIST to get 32% off Puori Grass-fed Whey Protein when you start a subscription.

Fatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and Fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.

LMNT Electrolytes: Our #1 electrolytes for optimal hydration, and their new 12oz sparkling cans are officially for sale online! Get a free Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

“I started doing my strength training at 55, so a few years back.”

“Fierce is... It’s a mindset.”

“At any age, whether you are 45 or 75, I believe it is never too late.”

Connect with Donnie Moss

Instagram: https://www.instagram.com/fitandfiercewithdonnie/

Website: https://fitandfiercewithdonnie.com/

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Click Here for the full interview transcript.

Say hi to the AGEIST team!