Sara Riggare and Joshua Biro discuss the current landscape and potential future directions of AI in primary care, including how it can empower patients, how we can see more human–AI collaboration, and how these aspects, alongside others, can affect patient safety.

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Sara Riggare: https://www.thelancet.com/journals/lanprc/article/PIIS3050-5143(26)00007-5/fulltext

Joshua Biro: https://www.thelancet.com/journals/lanprc/article/PIIS3050-5143(26)00010-5/fulltext

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Alike van der Velden, Marta Wanat, and Christopher Butler discuss the PRUDENCE trial, which assessed the ability of a point-of-care testing strategy to reduce antibiotic prescribing for acute respiratory tract infections in primary care. The trial includes a process evaluation, so the results (and this podcast) highlight both quantitative and qualitative data.

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https://www.thelancet.com/journals/lanprc/article/PIIS3050-5143(25)00104-9/fulltext
https://www.thelancet.com/journals/lanprc/article/PIIS3050-5143(25)00105-0/fulltex

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Erica Fong and Sarah Beale discuss their Lancet Primary Care Article on the effects of post-COVID-19 condition on daily functional activities, including the implications of their findings for real-world primary care and for future research and policy.

Oyungerel Byambasuren provides her lived-experience perspective, including on the Article, the effects of post-COVID-19 condition on everyday life, and the potential next steps for research into and management of post-COVID-19 condition in primary care.

https://www.thelancet.com/journals/lanprc/article/PIIS3050-5143(25)00093-7/fulltext

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Professor Dame Tina Lavender discusses her Lancet Primary Care Viewpoint regarding meaningful relational maternity care in low-income and middle-income countries, including barriers and facilitators, workforce training, and implications on subsequent antenatal care.

Click here to read the full article: https://www.thelancet.com/journals/lanprc/article/PIIS3050-5143(25)00069-X/fulltext

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Professor Dame Louise Robinson discusses her Lancet Primary Care Viewpoint regarding primary care perspectives on the new therapeutic era for Alzheimer’s disease, including implications for the health-care workforce, the potential for use around the work, and useful data that are currently lacking.

Click here to read the full paper: https://www.thelancet.com/journals/lanprc/article/PIIS3050-5143(25)00061-5/fulltext

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Konstantinos Balaskas and Anitta Sharma discuss the HERMES trial, a cluster-randomised controlled trial investigating teleophthalmology innovations versus standard of care, including real-world implications of the AI involved and potential directions for future research and practice.

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Patrick de Marie Katoto speaks on his first-hand experience of the ongoing mpox epidemic in DR Congo, including the essential involvement of primary care, current and future vaccine work, and bolstering health systems so they are equipped to manage both this and future epidemics.

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Francesca Ligori Malcolm discusses her Article exploring 1-year mortality among people having a faecal immunochemical test in English primary care for investigation of symptoms of suspected colorectal cancer, including the real-world implications of her findings and the many possible avenues for future research.

Read the full article:

https://www.thelancet.com/journals/lanprc/article/PIIS3050-5143(25)00007-X/fulltext?dgcid=buzzsprout_icw_podcast_August_25_lanprc

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