Weight and weight loss is something that we have struggled to understand properly for decades. Whether its a fad diet, a new theory or an alternative approach, it's something we have been discussing and often misunderstanding, for many years.

With the introduction of GLP1s, this has only increased.

GLP-1 medications have changed the conversation around weight, appetite and health in a way few of us could have predicted. But what happens before you start, while you're on them, and after?

Dr Fede Amati, who has joined us on The Midpoint before, is a Medical Scientist and Registered Public Health Nutritionist who has been at the forefront of the research into how food and our bodies interact — and her brilliant new book tackles one of the most talked about topics in health right now.

In this episode of Midpoint, Gabby sits down with Dr Amati for a conversation about what these medications actually do, why what you eat alongside them matters more than you might think, and how to build a relationship with food that serves you at every stage of life. No judgement, no fads — just really good science explained clearly.

Dr Fede Amati's new book, The Appetite Reset: How to Eat, Drink and Thrive Before, During and After GLP-1s, is published by Penguin Michael Joseph and is out now, priced £25.

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Although we speak a lot about women's health on The Midpoint, it's also important to look at men's health and what we should take notice of. Kenny's diagnosis changed a lot of things with regards to our awareness of health and proved that we should always get ahead of what can go wrong or actually look for the signs before something really does become an issue.

Today's guest is someone who is at the absolute forefront of Men's Health in this country. Professor Vaibhav Modgil is a Consultant Urological Surgeon at Manchester Royal Infirmary and one of the UK's leading experts in andrology — which is essentially the study of male health and the male reproductive system. He has just won one of the most prestigious awards in British urology and his whole career has been built around not just treating men, but understanding them.

He has introduced pioneering microsurgical techniques to the North West, and his specialist practice covers everything from erectile dysfunction and testosterone deficiency to complex reconstruction. He founded the Manchester Andrology Research Collaborative, has published over sixty academic papers, and has contributed to international guidelines on men's health across Europe and America. He is also Editor-in-Chief of Trends in Urology and Men's Health.

Whether this is relevant to you, or someone you care about, hopefully you will find something useful to take away.

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My guest today is someone whose life reads like a series of things most of us would consider utterly impossible.

Vicki Anstey is a world record holder, a human performance coach, an entrepreneur and an adventurer — and that only scratches the surface. She was one of the first women to reach the final stages of SAS Who Dares Wins, rowed the mid-Pacific unaided, and in 2024 cycled 3,000 miles across America in one of the toughest endurance races on the planet. She has raced 250 kilometres across the Arctic in minus 35 degrees and across the Savannahs of Kenya in 50 degree heat. Vicki is also a passionate advocate for girls and young women through her role as UK Ambassador for Inspiring Girls International.

She is a perfect Midpoint guest because at the heart of everything she does is a belief that we are all capable of so much more than we think — and her own life is the proof. Her brilliant new book, Other People Are Like The Weather, is published by Northside House and is out on the 17th of June in hardback from Waterstones and Amazon. You can also pre-order a signed and dedicated copy —https://vickianstey.co.uk/product/other-people-are-like-the-weather/

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