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Theoretical Neuroscience Podcast

Theoretical Neuroscience Podcast

By: Gaute Einevoll
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The podcast focuses on topics in theoretical/computational neuroscience and is primarily aimed at students and researchers in the field.2023 Biological Sciences Physics Science
Episodes
  • On neuronal identity and representational drift - with Timothy O'Leary - #42

    On neuronal identity and representational drift - with Timothy O'Leary - #42
    Jun 20 2026
    A bursting neuron can maintain its firing-pattern identity throughout an animal's life, even though the ion-channel proteins underlying this identity are turned over on the timescale of days. Today's guest has proposed that neuronal identities are stored in the specific protein production rules, which are regulated by intracellular calcium signaling. And how can animals reliably perform a learned task for weeks, even when the underlying neural representation drifts over time, so-called representational drift?
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    1 hr and 44 mins
  • On functional effects of neuronal heterogeneity - with David Dahmen - #41

    On functional effects of neuronal heterogeneity - with David Dahmen - #41
    May 23 2026

    Most neural network models till date have assumed all neurons to be identical, or at least that all neurons within a population are identical. In reality, no two neurons are completely the same.

    Is this due to unavoidable "biological noise" that the nervous system has to cope with, or can it be a useful feature included by design?

    The guest co-wrote the recent paper "How heterogeneity shapes dynamics and computation in the brain" addressing this question.
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    1 hr and 30 mins
  • On smelling your way to the fruit with ring models - with Katherine Nagel - #40

    On smelling your way to the fruit with ring models - with Katherine Nagel - #40
    Apr 25 2026

    Fruit flies need a short-term (working) memory to keep their direction when they navigate their way to the fruit by smelling.

    Mean-field ring models was theoretically suggested to encode stimulus orientations 30 years and was observed in fruit-fly compass neurons 10 years ago. But how does odor input come into the picture to set the compass course?

    The group of the guest has studied the question with a host of different experimental and theoretical methods.
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    1 hr and 25 mins
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