Brady and Thomas delve into antioxidants, reviewing the ISSN's recent position statement on antioxidants: benefits, drawbacks, and reviewing supplements by efficacy

Brought to you by ProBio Nutrition - your all-in-one daily supplement for runners. Get 40% off with code RLRH (or an extra 10% off + free shipping with a subscription) ➡️

https://bit.ly/ProBioRLRH

00:00 Introduction

01:30 The role of antioxidants

05:05 Where we get antioxidants from

06:50 Hard training and antioxidant needs

08:55 Hormesis effect, risk of ‘blunting’ adaptation

12:47 AD ProBio Nutrition

15:00 Introducing the ISSN Supplement List

17:44 High Evidence (Creatine, Beetroot, Tart Cherry)

23:10 Moderate Evidence (Omega-3, Astaxanthin, Blackcurrant)

27:20 Lower Evidence (Ashwagandha, Glutathione, Green Tea, Pomegranate)

35:00 Weak-Low Evidence (Urolithin-A, Sulforaphane, Curcumin)

38:42 Takeaways - When Runners Should Take Antioxidant Supplements

39:00 Post-marathon antioxidants

40:41 Multi-day hard exercise antioxidants

Brady’s article on the discussion:

https://runlongrunhealthy.substack.com/p/should-runners-take-antioxidant-supplements

Run Long Run Healthy is brought to you by Marathon Handbook.

➡ https://marathonhandbook.com

Subscribe to the Run Long Run Healthy podcast:

➡ Spotify: https://bit.ly/RLRH-spotify

➡ Apple podcasts: apple.co/43iqUKx

Get the RLRH weekly newsletter (choose free or paid):

➡ https://marathonhandbook.com/run-long...

➡ https://runlongrunhealthy.substack.com/

Follow us online:

BRADY ON X ➡ https://x.com/B_Holmer/

PHYSIOLOGICALLY SPEAKING (Brady's Newsletter) ➡ https://www.physiologicallyspeaking.com/

MARATHON HANDBOOK IG ➡ / marathon.handbook

Brady explains a new study that looks at the effect that endurance exercise has on the brain, both during and after exercise - and the potential implications for how runners should think about the post-run window.

00:00 The brain’s role in running

02:00 Describing the study: measuring brain activity during

05:40 findings: What happens in the brain during and after exercise

13:10 ProBio Nutrition (ad)

14:29 Does this work in humans? And neurodoping

16:05 Takeaways for runners: allow a window for recovery

20:18 Can we hack the brain?

Brady’s article on the discussion:

How Exercise Hardwires the Brain for Endurance

https://www.physiologicallyspeaking.com/p/physiology-friday-306-how-exercise

The study:

Exercise-induced activation of ventromedial hypothalamic steroidogenic factor-1 neurons mediates improvements in endurance

https://pubmed.ncbi.nlm.nih.gov/41687612/

Run Long Run Healthy is brought to you by Marathon Handbook.

➡ https://marathonhandbook.com

Subscribe to the Run Long Run Healthy podcast:

➡ Spotify: https://bit.ly/RLRH-spotify

➡ Apple podcasts: apple.co/43iqUKx

Get the RLRH weekly newsletter (choose free or paid):

➡ https://marathonhandbook.com/run-long...

➡ https://runlongrunhealthy.substack.com/

Follow us online:

BRADY ON X ➡ https://x.com/B_Holmer/

PHYSIOLOGICALLY SPEAKING (Brady's Newsletter) ➡ https://www.physiologicallyspeaking.com/

MARATHON HANDBOOK IG ➡ / marathon.handbook

Brady Holmer sits down with Dr. Marc Bubbs — performance nutritionist, author, and creator of ProBio Nutrition — to break down everything runners need to know about gut health. From identifying food triggers to fueling on race day without GI disaster, Dr. Bubbs shares 20+ years of experience working with Olympians, pro athletes, and everyday runners. Whether you're dealing with chronic bloating or trying to push your carb intake past 60g/hour, this episode has you covered.

Brought to you by ProBio Nutrition - your all-in-one daily supplement for runners. Get 40% off with code RLRH (or 50% off + free shipping with a subscription) ➡️

https://bit.ly/ProBioRLRH

📚 Dr. Bubbs' books: Peak and Peak 40

🌐 drbubbs.com | probionutrition.com

📱 Follow Dr. Bubbs on Instagram & YouTube: @drbubbs

0:00 Introduction & Dr. Mark Bubbs' Background

1:07 Crossover Between Elite Athletes & General Population

2:04 Gut Health as a Buzzword — What Does It Actually Mean?

2:47 The 4 Pillars of Good Gut Health (King's College Framework)

5:47 Three Gut Health Scenarios: Poor → Good → Great

6:19 Scenario 1: Red & Yellow Flags — When to See a Doctor

9:14 The Difficulty of Identifying Problem Foods

9:54 Exercise-Related vs. Everyday GI Symptoms

11:42 Why You Should Start With Breakfast

12:07 The 3-4 Hour Detective Method

13:59 Can GI Symptoms Actually Be Resolved?

15:02 Eating Out vs. Cooking at Home

16:09 Are Food Sensitivity Tests Worth Your Money?

18:37 Scenario 2: When Running Triggers GI Distress

19:48 How Getting Fitter Improves Gut Diversity

20:57 GI Symptom Rates: Ultras, Ironman, Team Sports & Running

22:50 Finding Your Carb Intake Inflection Point

24:17 Gut Training: Titrating Up From 60g/hr

25:36 Is Pushing Above 80g/hr Worth the Risk?

26:00 Fueling Advice for Slower Marathon Runners

26:56 — AD BREAK —

28:08 Best Ways to Train Your Gut

29:06 Race Day Anxiety & the Gut-Brain Connection

31:20 Building Gut Health Over Months of Training

31:41 The 30 Food Diversity Challenge

33:08 Does Getting Fitter Reduce GI Symptoms? (The Bell Curve)

35:12 Probiotics for Colds, Travel & Performance

36:30 Race Week & Race Morning: What to Do and Avoid

38:47 Pro Tip: Caffeinated Gum Before the Start Line

39:06 The Golden Rule — Don't Try Anything New on Race Day

39:30 Carb Mouth Rinsing: The Placebo That Works

40:00 Scenario 3: Optimizing Gut Health for Performance

41:08 Prebiotics Explained — Seeds for Your Gut Garden

43:47 Best Whole Foods for Gut Health (By Category)

46:28 The Truth About Processed Food & Your Gut

47:47 Knowledge vs. Execution: The Real Friction Point

49:00 ProBio ProBlend: Why Dr. Bubbs Created It

53:00 Where to Find Dr. Bubbs, His Books & ProBio

Thomas and Brady discuss the potential negative effects of long-term running on your heart, and the potential increase in mortality risk. How worried should regular runners be?

Brought to you by ProBio Nutrition - your all-in-one daily supplement for runners. Get 40% off with code RLRH (or 50% off + free shipping with a subscription) ➡️https://bit.ly/ProBioRLRH

00:00 What does decades of running do to your heart?

03:53 The physical changes in your heart

06:10 Calcium

07:50 How much running causes these changes?
09:11 Stress and the heart

11:11 “Show me the bodies” - mortality risk?

15:28 “wear and tear” - valid?

18:18 - signs and symptoms of heart issues

23:20 Men and women, the differences

24:50 Study - masters athletes training vs heart episodes

32:45 Has Brady changed his training based on potential future heart issues?

The study referenced:
The timing and relationship of ventricular arrhythmia with exercise patterns in veteran male endurance athletes

https://academic.oup.com/eurjpc/advance-article/doi/10.1093/eurjpc/zwag021/8417747

Run Long Run Healthy is brought to you by Marathon Handbook.

➡ https://marathonhandbook.com

Subscribe to the Run Long Run Healthy podcast:

➡ Spotify: https://bit.ly/RLRH-spotify

➡ Apple podcasts: apple.co/43iqUKx

Get the RLRH weekly newsletter (choose free or paid):

➡ https://marathonhandbook.com/run-long...

➡ https://runlongrunhealthy.substack.com/

Follow us online:

BRADY ON X ➡ https://x.com/B_Holmer/

PHYSIOLOGICALLY SPEAKING (Brady's Newsletter) ➡ https://www.physiologicallyspeaking.com/

MARATHON HANDBOOK IG ➡ / marathon.handbook

Thomas sits down with Marco Altini, prominent researcher in HRV, advisor to Aura, and dedicated ultrarunner, to discuss one of the most talked-about metrics in the running world today: Heart Rate Variability.

Marco's Substack:

https://marcoaltini.substack.com/

Marco's series of guides to HRV for runners on Marathon Handbook:

https://marathonhandbook.com/heart-rate-variability-guide/

00:00 3 things I learned

01:54 What does HRV measure

05:50 RHR vs HRV

07:50 Why everyone's HRV is different

09:45 What runners can use HRV for

11:10 Other ways to increase HRV

12:50 How to reliably measure HRV

15:18 Sleeping vs awake HRV

18:25 Best devices for measuring HRV

20:00 limits of HRV reporting

23:38 Future / tech limits of HRV interpretation

25:12 Winter lowers HRV

29:12 how Marco uses HRV in his run training

32:36 Marathon / ultramarathon recovery using HRV

Brady sits down with TrainingPeaks founder Dirk Friel discuss the future of endurance science, how coaching is evolving with technology, why AI can assist coaches but not replace them, and what is coming in the next 12 months.00:00 Dirk's background05:50 the birth of TrainingPeaks10:34 evolving use of data in endurance sports20:39 the durability metric28:00 shoe tracking30:00 human vs AI coaching42:00 Coaches using AI48:00 Emerging trends in endurance57:20 TP integrating sleep and nutrition 1:03:25 TP upcoming community and virtual featuresRun Long Run Healthy is brought to you by Marathon Handbook.➡ https://marathonhandbook.comSubscribe to the Run Long Run Healthy podcast:➡ Spotify: https://bit.ly/RLRH-spotify➡ Apple podcasts: apple.co/43iqUKxGet the RLRH weekly newsletter (choose free or paid):➡ https://marathonhandbook.com/run-long...➡ https://runlongrunhealthy.substack.com/Follow us online:BRADY ON X ➡ https://x.com/B_Holmer/PHYSIOLOGICALLY SPEAKING (Brady's Newsletter) ➡ https://www.physiologicallyspeaking.com/MARATHON HANDBOOK IG ➡ / marathon.handbook

What is ergodicity and how can it help you plan for longevity in your running? That's the topic Thomas is exploring in today's episode, where he looks at how it can apply to single races, seasons, or your whole life - and why you should be more like Haruki Murakami and less like David Goggins00:00 Introducing ergodicity01:16 What is ergodicity?03:25 David Goggins - non-ergodic05:19 Haruki Murakami - ergodic06:58 My big fat ergodic podium win in Namibia08:20 Tortoise and Hare08:45 Why timeframe matters10:35 The price of a non-ergodic approach long-term11:30 How to apply ergodicity to your running - 4 tips

In this episode, Brady and Thomas discuss a new study that showed marathon runners were consistently consuming less carbohydrates during their race than they either planned or perceived; why this is happening, why it’s important for runners to be aware of this, and how to avoid it.The RLRH Substack post on this article:https://runlongrunhealthy.substack.com/p/why-marathoners-keep-missing-theirThe study:Under Consumed and Overestimated: Discrepancies in Race-Day Carbohydrate Intake Among Endurance Athleteshttps://onlinelibrary.wiley.com/doi/10.1002/ejsc.70055Run Long Run Healthy is brought to you by Marathon Handbook.➡ https://marathonhandbook.comSubscribe to the Run Long Run Healthy podcast:➡ Spotify: https://bit.ly/RLRH-spotify➡ Apple podcasts: apple.co/43iqUKxGet the RLRH weekly newsletter (choose free or paid):➡ https://marathonhandbook.com/run-long...➡ https://runlongrunhealthy.substack.com/Follow us online:BRADY ON X ➡ https://x.com/B_Holmer/PHYSIOLOGICALLY SPEAKING (Brady's Newsletter) ➡ https://www.physiologicallyspeaking.com/MARATHON HANDBOOK IG ➡ / marathon.handbook00:00 Intro'ing the topic01:20 The importance of carbs during the marathon03:51 the study, explained08:50 perceived vs actual carb intake12:18 How sleep and anxiety play a role15:48 GI issues a factor?17:30 How this study has influenced Brady's fuelling strategy